Chrislaine Withers-Martinez Selected Research

Subtilisin

1/2020	A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1.
5/2014	The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
3/2013	Molecular determinants of binding to the Plasmodium subtilisin-like protease 1.
5/2012	Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target.
7/2004	Subtilisin-like proteases of the malaria parasite.

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Chrislaine Withers-Martinez Research Topics

Disease

24	Malaria 01/2021 - 08/2002
4	Rupture 01/2021 - 03/2011
3	Disease Progression 01/2021 - 05/2014

Drug/Important Bio-Agent (IBA)

9	Peptide Hydrolases (Proteases)FDA Link 01/2020 - 08/2002
8	Serine Proteases (Serine Protease)IBA 01/2021 - 08/2002
5	Antimalarials (Antimalarial Agents)IBA 01/2021 - 05/2012
5	SubtilisinIBA 01/2020 - 07/2004
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2009
3	CalciumIBA 01/2021 - 08/2002
3	AntibodiesIBA 12/2011 - 08/2002
2	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021 - 11/2005
2	Cysteine Proteases (Cysteine Protease)IBA 01/2021 - 11/2012
2	SpectrinIBA 01/2021 - 10/2015
2	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 01/2021 - 05/2013
2	Pharmaceutical PreparationsIBA 02/2019 - 05/2012
2	Merozoite Surface Protein 1 (MSA1)IBA 10/2015 - 11/2005
1	Boronic AcidsIBA 01/2021
1	Serine (L-Serine)FDA Link 01/2020
1	plasmepsin (plasmepsin I)IBA 02/2019
1	Cyclic AMP (AMP, Cyclic)IBA 01/2019
1	Phospholipids (Phosphatides)FDA LinkGeneric 11/2013
1	Malaria VaccinesIBA 12/2011
1	Carrier Proteins (Binding Protein)IBA 09/2006
1	LigandsIBA 09/2006
1	Subtilisins (Subtilopeptidase A)IBA 08/2002
1	EnzymesIBA 08/2002
1	DisulfidesIBA 08/2002
1	Cysteine (L-Cysteine)FDA Link 08/2002
1	AntigensIBA 08/2002
1	VaccinesIBA 08/2002